It feels like Apple are having the same questions. Do we want a full screen app browser that takes up the entire screen? One where you can't drag multiple items and instead have to drag things around one by one? In 2022, it feels like the traditional computer - especially the Mac - is having a bit of a renaissance. Launchpad was one of Mac OS X's biggest tablet-esque features, while Windows 8 went the whole hog (some would say they went too far). Desktop OS's felt the need to incorporate tablet inspired UI elements. Back in 2011 when it was implemented in Mac OS X Lion, it was at a time when smartphones and tablets were new and exciting. It's also just as convenient as Spotlight when it comes to finding apps thanks to the search box.ĭespite this, I think the Launchpad was a product of its time. I personally find Launchpad to be very useful when you want a clean Dock, and like to visually search for apps (like if you want an app but don't know the name of it). Newcomers to macOS generally use the Dock. Most people who've been using macOS extensively use Spotlight or some other alternative (like Alfred) to access their apps. Some would argue it's redundant and has been for some time. What do we think of Launchpad, and where do we think it's going in future versions of macOS?
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" is still a growing company and a lot of it just comes down to bandwidth," Walker said during the discussion at the meeting. However, Pazdur revealed that the company hadn't initially set out to submit registrational data on tucatinib nearly simultaneously to multiple regulatory bodies through Project Orbis and had to "scurry" to do so. Luke Walker, VP of clinical development at Seagen, noted that the 600-patient, registrational HER2CLIMB trial for tucatinib enrolled patients in the US, Canada, Australia, and 11 European countries, including Switzerland. Seagen's tucatinib (Tukysa), which the FDA approved last year in combination with trastuzumab (Genentech's Herceptin) and capecitabine for HER2-positive, metastatic breast cancer, is an example of a precision oncology drug that regulators in the US, Switzerland, Singapore, Australia, and Canada collaboratively reviewed within Project Orbis.ĭuring the second session of the American Association for Cancer Research's annual meeting last month, Richard Pazdur, director of the FDA's Oncology Center of Excellence, moderated a discussion with the regulatory, academic, and industry experts involved with the tucatinib development program and provided an inside look at how the Project Orbis review process works and the impact it is having. Angelo de Claro, associate director for global clinical sciences at the FDA's Oncology Center of Excellence, told Precision Oncology News last week that 35 of those 38 approved drugs were targeted therapies and 10 were drugs indicated for molecularly defined patient populations. Currently, regulatory authorities in six countries are participating with the FDA in the project: Australia's Therapeutic Goods Administration, Health Canada, Singapore's Health Sciences Authority, Switzerland's Swissmedic, Brazil's Health Regulatory Agency (or Agencia Nacional de Vigilancia Sanitaria), and the UK's Medicines & Healthcare Products Regulatory Agency.įrom June 2019 to June 2020, before the UK's MHRA joined earlier this year, Project Orbis received 60 marketing applications for cancer drugs, and the participating regulatory agencies approved 38 applications. The FDA's Oncology Center of Excellence launched Project Orbis in 2019 as a collaboration between regulators in multiple countries who jointly review cancer drugs with the goal of expediting access to innovative therapeutics globally. NEW YORK – The US Food and Drug Administration's Project Orbis, a pathway through which drugmakers can launch their cancer therapies in different countries in quick succession, is helping other nations gain access to precision oncology treatments months, sometimes years, earlier than they would have otherwise. Also, please follow the guidelines of publisher and editors provided below.This article has been updated to note that the company previously known as Seattle Genetics is now called Seagen. The final version includes names and acknowledgments. If a manuscript is accepted, the editors request a file with the final version. The editors attempt to reach a decision within 3 months of the submission of the manuscript. The author is informed of the decision by email. The review process can result in acceptance, the recommendation of revisions or rejection of the manuscript. by acknowledgments and self-references in footnotes).Īll submissions are subjected to double blind peer review. Please pay attention to the anonymization of your text so that your identity as author cannot be ascertained directly or indirectly (e.g. In initial submissions, the citation rules of the journal do not have to be strictly followed. A manuscript submitted to the journal must be ready for publication, the editors do not accept partial or draft versions. During the review process, manuscripts may not be submitted elsewhere. Submissions must be original articles (no translations) which must not be previously published. Please send manuscript submissions to the editor-in-chief. The album’s opening track, Evolution Road, might be the best example of this: I got chills – actual shivers of awe – when I heard Zal roar, “My fingertips, my Holy Fire!” A lyrical tip o’ the hat to the much-missed Alex Harvey, whose Faith Healer imagery is seared into the soul of every SAHB fan. Once again (as he did with Sin’Dogs), Zal proves that in addition to his renowned fretboard abilities, he’s also a ferociously effective frontman. Ellipsis is a barnstormer of an album – fearlessly creative, expressive and cathartic. I didn’t know exactly what to expect, but I knew it would be special. So I was excited to hear about his Orphans of the Ash project. How can he do this? How is it even possible? It shouldn’t be. In a live setting he does the impossible: makes perfect songs sound even more so. (Zal’s guitar work didn’t exist alone in those grooves, of course – there was a beautiful musical synergy between him and his bandmates Alex, Chris, Ted and Hugh.) I’ve been lucky enough to see Zal play live a bunch of times, both with SAHB and also with his Zal Cleminson’s Sin’Dogs project. One only has to play the SAHB discography (preferably on vinyl) on a quality hi-fi system to hear guitar sounds so unique, so inspired, so tasteful, so rich in nuance and melodic genius, that the listener is forever changed for the better. He’s a wizard, I tell you! This fact is well known by fans of The Sensational Alex Harvey Band. There are plenty of guitar maestros, but Zal is the guitar wizard. No one else can do what he can do with a guitar. The most impressive of all was Zal Cleminson. Most of them were impressive, some jaw-droppingly so (Vai, Malmsteen, Satriani, Gilbert, Van Halen, Skolnick, and many others). Since my first metal gig as a primary-school kid (Iron Maiden at Glasgow Apollo), I’ve seen thousands of guitarists playing live. For an exhilarating example, listen to I Name You Under Our Cult, which (like Rotting Christ’s Elthe Kyrie) starts out chaotic and leaves the listener wondering where the hell the song is going, then the HUGE chorus arrives with its untamed Tolis growl, cascading layers of glorious guitar, and a rumble of drums that could collapse castles. During his long career with Rotting Christ, Sakis has pioneered, honed and perfected a unique sonic blueprint, which he carries on with this solo release. From the spoken words that kick off opening track My Salvation to the closing refrains of final song Nocturnal Hecate (a cover of the Daemonia Nymphe track), this album is pure atmospheric perfection. The walls of hypnotic riffage are present in force, as is Sakis’s distinctive growl, his monk-like chanted backing vocals, and those immersive lyrics, which, as they also have on recent RC releases, explore numinous territory. Musically and thematically, the material on AtFoH is just like latter-day Rotting Christ. The moniker doesn’t matter, though – it’s the music that counts. I’m not sure why Sakis chose to release this as a solo album rather than a Rotting Christ release. As I listened to Among the Fires of Hell for the first time, I knew I was hearing my album of the year, a record so immaculate that its place at the top of my 2022 list was guaranteed. More than 1,000 tons of the sedimentary rock (oolite limestone) was quarried and sculpted into a variety of shapes, including slab walls, tables, chairs, a crescent moon, a water fountain and a. In these partition walls, the potential of a screen block is maximized: it’s open design provides ventilation, partial shading, privacy, and a decorative break in the monotony of the wall’s surface. We have 12 styles of Screen Block and many colors available, each manufactured to the highest standard. Some profiles of Architectural Screen Blocks are special order, please call our sales team for details. Oolite Stone is made up of small spheres called ooiliths that are stuck together by lime mud. We deliver all profiles Nationwide call for delivery 6 days a week. You may know it as Maracuya, grenadya or passion fruit.They form when calcium carbonate is deposited on the surface of sand grains rolled (by waves) around on a shallow sea floor. Purple passionflower ( Passiflora incarnata) has a round yellow fruit that is super tasty. Instead, humans love passion vines for their beautiful flowers and their delicious fruit. Passion leaves might be lunch for caterpillars, but they don’t taste good to humans and other animals. Passion vines ( Passiflora spp.) of all species are the food that our caterpillars eat the most, and where we lay our eggs. Did you know, most butterflies only live for a week or two, but we live for several months! Pollen gives us the strength to live a long life. Nectar is mostly sugar, but pollen is full of vitamins and protein. It also has lots of pollen, which we love! All butterflies drink nectar, but we Heliconians like to eat pollen as well. We Heliconians all love the Oolite room because it has our two favorite foods– Corkystem passion vines ( Passiflora suberosa) and firebush flowers ( Hamelia patens)! Firebush has delicious nectar that is a favorite for butterflies, bees, and even hummingbirds. But be careful to look at us with your eyes only! Catching us with your hands hurts our delicate wings. We fly a bit slower than other butterflies so it is easy to see us gently gliding by. And then look up and see if you can spot us as butterflies. Take a look around and see if you can find us munching away on leaves. And guess what? Our caterpillars look like little aliens with spiky white or orange bodies and black spots. Can you guess which animal they look like? That’s right, a zebra! These butterflies are covered in stripes, but instead of black and white, they have black and yellow stripes. Zebra longwing butterflies are the easiest to find. They also have pretty white spots you can see when our wings are closed and black spots on their upper wing areas. Gulf Fritillaries are also orange but have a block chain pattern along the edges of their wings. Julias have beautiful orange wings and look almost like leaves. We look similar in size and shape, but we have a few ways you can tell the difference between us. We are all members of a group of butterflies called the Heliconias, so the three of us are like cousins. Here in the Oolite Room, you can spot three native butterflies– we are the Zebra Longwing ( Heliconius charithonia), Julia ( Dryas julia), and Gulf Fritillary ( Agraulis vanillae). The featured bloggers are Modavracha and Jodie’s Touch of Style because we loved their Kimonos from last week’s linkup!Īdd your link below and make sure to follow the theme for your chance to be featured on our blogs. Walking in Memphis | The Fashion Canvas | Sew Sarah R What is your favorite item from Socialite? How do you style your own tie dresses? Let me know in a comment below!ĭress c/o // Sandals // Earrings // Ring c/o Since I love this dress from Socialite so much, I have teamed up with them to give away 4 of them to some lucky readers! It will be the exact dress in the black and white polka dot version, and it’s so perfect for summer! To enter, just use the rafflecopter widget below and good luck! Semi-stretch dress Spaghetti strap Sweetheart neckline Wired Short lining Slit Ruffles Rhinestones 95 Polyester 5 Spandex Hand wash cold. And I just love the bright coral orange color! I don’t typically do the whole tie top with a cutout at the waist, but I was able to tie it enough that I felt like it wasn’t too revealing if you typically shy away from tie dresses pieces like I do. Use of the card constitutes acceptance of these Terms and Conditions issued by FULLBEAUTY Brands, Inc.Happy Tuesday! This is one of those tie dresses that I saw and thought it would be SO cute on other people but not on me! Once I tried it on, I was pleasantly surprised.
Follow the instructions on-screen until you reach the macOS Monterey desktop screen.Ĭongratulations, you are now an Apple developer testing the latest macOS Monterey! Click the button and click on Continue to proceed with the installation. In the Installer window, when you click Continue, you'll trigger the Software Update window, where you should be able to see an Upgrade Now button. Apple has released a list of devices macOS Monterey 12 supports: Is Your Device Supported by macOS Monterey?Įven before you get a developer account from Apple, you should check if your device is eligible for an upgrade to the new OS version. Make sure you know how to do that and download the installer for that version on a DVD or USB drive beforehand. In this case, that might be macOS Big Sur or an older one like Catalina or Mojave. The only way to retrieve your data would be to do a factory reset or attempt to roll back to an older, stable version of the OS. The reason is obvious but, in case you're new to the beta scenario, you should be aware that beta versions are notoriously buggy and could compromise your entire system. There a rule of thumb before downloading and installing any beta version of an operating system: NEVER do it on your primary device - the one you use for work and other important purposes. Things You Need to Do before Download macOS Monterey Do Not Use Your Primary Device Part 3: The Best UI/UX Design Tool for macOS Monterey.Part 2: How to Download and Install macOS Monterey Beta.Part 1: 4 Things to do before Download macOS Monterey.However, if you're new to the game, there are several things you should know before you install macOS Monterey beta on your device. If you're a developer or even if you have an Apple Developer account, you can get the installation package. MacOS Monterey, the latest desktop operating system from Apple, is now in its first developer beta. The sea snail is okay when it eventually becomes visible through the smoke although not as amazing as we are led to believe, but the giant lunar moth is quite a disappointment, as it is just a person in a costume with feeble wings attached, hanging from a wire. Others are not so good and look a little like stuffed toys. Some smaller animals that look really good include Gub-Gub the pig, who moves just like a Muppet animal but no longer goes on the voyage, Sheila the fox, Sophie the seal, a duck, a pair of sheep and a lobster. There are some other really good larger animals, including the dancing Pushmi-Pullyu, an elephant and a baby mammoth, plus the two fantastic orang utans that only come on to dance the finale. Jip the old English sheepdog is a full costume containing James Deverell, but this is a long way from Dick Whittington's cat and looks and moves incredibly like a real dog. Most of those that remain in the show are absolutely wonderful and threaten to steal the show from the humans. The other big stars of the production are the animals, supplied in the original West End production by Jim Henson's Creature Shop. Other notable performances come from David Anthony and Joanna Lee Martin who are extremely good as circus owners Alfred and Gertie Blossom, Ako Mitchell is great as Straight Arrow and Halcro Johnston bellows appropriately as bad-tempered magistrate General Bellowes. Joanna Forest, playing Tommy, isn't remotely convincing as a young boy, which is probably more of a reflection on a poor casting decision than on her performance. He has very good support in the excellent Abigail Jaye as love interest Emma Fairfax, and Conor Michael-Sheridan is perfectly fine in his much-reduced role as Matthew Muggins and shows he has a very good voice in the bits of songs he still has left. Tommy Steele is superb in the title role, demonstrating that he can still play a substantial musical comedy role even as he approaches his 71st birthday next month. Polynesia's interjections in Talk to the Animals have gone, Dolittle has a whole verse of I've Never Seen Anything Like It before Blossom and Gertie and their circus even appear on stage and Dolittle has stolen Matthew's act one finale song After Today and Matthew's contribution to Where Are The Words?, changing the romantic plot completely. However there are changes to the show itself, with songs cut ( The Vegetarian has gone) and many others changed to make Dolittle's contribution to them substantially larger. It is not unusual to see a reduction in the scale of a production for a tour, and there are certainly big cuts in the scenery and the number and involvement of the animals in the action. This version of the show has been altered quite a bit from the 1998 stage original. Love interest is provided by the niece of the magistrate who, of course, finds him rude and frustrating at first but grows to love him. After a run-in with the local magistrate, Dolittle is helped to escape from gaol by a friendly circus elephant and goes on a voyage to find the great pink sea snail. His parrot, Polynesia, begins to teach him animal languages, and he decides to become an animal doctor. The rest of the book is about the doctor's efforts to communicate with the moth, while keeping the public away.Leslie Bricusse's famous musical version of the classic children's novels by Hugh Lofting about a man who can talk to animals in their own languages comes to Manchester starring the irrepressible Tommy Steele.ĭoctor Dolittle is a doctor who doesn't really like people very much and so struggles to earn a living, not helped by the fact that his patients have to negotiate his personal and varied menagerie whenever they come to see him. Fascinated, he plans a voyage to find them, but one of the giant moths appears in his garden. The doctor also begins to hear talk about the Giant Moths. He begins to hear many fascinating stories, particularly one about a water beetle who was taken to Brazil in a clod of mud on a duck's foot. In the second part of the book, because his garden is teeming with insects, Dolittle decides to learn their language and contrives an apparatus that will allow him to do this. Some of the dogs tell the stories of their lives over dinner. In the first part of the book, Doctor Dolittle's assistant, Tommy Stubbins, reports on Professor Quetch, curator of the Dog Museum in the Home for Crossbred Dogs. Doctor Dolittle's Garden (1927) is the eighth book in Hugh Lofting's Doctor Dolittle series of children's books. 20-inch sparklers are perfect for most of our wedding needs.ġ4-inch sparklers are perfect for all intimate to medium-sized weddings and are guaranteed to provide plenty of time to capture the bride and groom's dream wedding exit. This gives us plenty of time to be able to slowly exit our wedding in a calm and unhurried manner. Each 20-inch wedding sparkler has a 2-minute burn duration. They are also double dip processed and produce a bright and cheerful gold sparkle. If we want to go all out, we should choose a 36-inch wedding sparkler.Ģ0-inch sparklers are the most affordable wedding sparklers we can buy. If we choose a 36-inch sparkler we are sure the bride and groom will get the amazing experience they always dreamed of for their big day. They also give enough time if we want separate photos, with different groups. Our wedding sparklers are triple dipped and can last 3+ mins giving us an abundance of time for pictures while the bride and groom is entering, exiting, and kissing. Learn how to spot quality wedding sparklers for your grand wedding exit.ģ6-inch sparklers are the longest lasting sparklers we have available. As we are figuring out when to order wedding sparklers, one question we have is how long do wedding sparklers last? Will they last long enough for our celebration, or will they fizzle out before we are ready? In truth how long a sparkler will burn depends on which sparkler was chosen for the big celebration. In many cases these sparklers are used to highlight the bride and groom as they leave the church or wedding venue. As the bride and groom work to make sure everything is perfect for their big day, more and more of them are choosing to use wedding sparklers to add that something extra and to make their wedding a truly spectacular celebration. We work hard to make sure we have the perfect dress, perfect cake, perfect location, and perfect decorations. A wedding is a grand experience that we want etched into our memories for all our lives. It’s notable that Long Island jamband opened at Penn’s Peak on Friday, and the group’s guitarist Jared Cowen spun the wheel as a child back in 2007. We had the wheel slightly leaning towards old songs bustouts, 7-5 or 8-4, but the wheel wanted the new stuff! “Orch theme” and “Portal.” He went on to jubilantly add, “We had the wheel slightly leaning towards old songs bustouts, 7-5 or 8-4, but the wheel wanted the new stuff!” The Disco Biscuits’ party of chance and display of improvisational skill continued as they moved from “Evolve” to “Hot Air Balloon” into a set-closing performance of “Why We Dance.”Īfter a short break, the band returned to the stage and decided to take fate into their own hands by picking a song of their choosing from the wheel for their last jam of the evening and went with “Floes,” which was last played at the Wellmont Theatre in Montclair, N.J., in November of 2021.Īfter the set, the Disco Biscuits’ Marc Brownstein took to Twitter to let everyone know which songs the wheel didn’t land on: “Crickets,” “Nughuffer,” “Floes,” (encored anyway), “Trooper” The second set, too, started with a whirl landing on an opener of “Lake Shore Drive” into “Running Into the Night.” As they played, around and around, the wheel went landing on “Barfly” and then “Tourists (Rocket Ship).” The possibility of major bust-outs remained as songs like “Trooper,” which hasn’t been played since 2014, were written on the board. Without pause, the wheel was spun twice more, leading into a jam of “Another Plan of Attack” into “Astronaut” to close the first set. The group debuted the concept of allowing a wheel to determine what song they’d play next back in Atlantic City in 2002 and have since used the wheel for shows only twice since: in Sayreville, N.J., in 2007 and New York’s PlayStation Theatre (now the Palladium Times Square) in 2016.Īfter their first spin, the Disco Biscuits opened with a jam of “Space Train” into “Pimp Blue Rikki.” Next, fate or luck decided the band play a bust out of “Park Ave,” which was last played on July 15, 2016, or 234 shows prior. Jerry Harrison and Adrian Belew Drop Summer 2024 Remain in Light Tour Dates with Cool Cool Coolīob Weir and Wolf Bros.On Saturday, the Disco Biscuits brought their Wheel Concept back to the stage at the beautiful mountaintop venue Penn’s Peak in Jim Thorpe, Pa. Watch: Paramount+ Drops Official Trailer for New Willie Nelson Docuseries The Allman Betts Family Revival Celebrate Dickey Betts’ 80th Birthday in Sarasota Learn more and find tickets to BISCOLAND here. Tickets and passes will go on sale starting Friday, July 14, at 10 a.m. In addition to access to the festival, camping passes and various transportation options such as RV parking and shuttle services will also be available. Music enthusiasts will have the opportunity to secure their spots at BISCOLAND with the Early Bird GA and VIP Weekend Packages. Performances include four sets by The Disco Biscuits, two sets by Lotus, along with an impressive roster of artists, including Emancipator, Papadosio, Opiuo, Sunsquabi, The Floozies, Eggy (who will perform two sets), Maddy O’Neal, Space Bacon, and a special Spaga Plays Dead set featuring Aron Magner of The Disco Biscuits. The inaugural lineup for BISCOLAND features an array of long-time friends and collaborators from the jam, jamtronica, and electronic music scenes. The Disco Biscuits’ Marc Brownstein expressed his enthusiasm for the upcoming event, stating, “2 nights in central New York with our Biscuits family, a carefully curated lineup, a blank canvas, a new beginning – that is a dream for the band and our community.” The news of BISCOLAND comes hot off the heels of the band’s captivating three-night run in the woods of Montana, which included incredible long-form, improvisational performances and tender sense of community for fans. The gathering’s website describes the location as a space where concert-goers can “create new connections through a love of music and nature in a pristine landscape of lush forests, spectacular waterfalls, and glorious vistas.” The new event space, campground, and concert venue nestled in the rolling hills of Central New York’s Apple Valley will set the stage for a weekend of unforgettable music and community.īISCOLAND marks a fresh chapter for The Disco Biscuits as they bring their signature sound and energetic performances to this carefully curated festival experience, which follows the lifelong memories of events they’ve curated in the past, including many Camp Biscos and, more recently City Bisco. 6 and 7, the jubilee will be held at the otherworldly Wonderland Forest in Lafayette, N.Y. The pioneering trance-fusion band, The Disco Biscuits, have unveiled exciting plans for a brand new two-day festival-style BISCOLAND. All employees must comply with Company, Division, and Store policies and applicable laws. The above statements are intended to describe the general nature of work performed by the employees assigned to this job and are not the official job description for the position. The company is publicly owned with supermarkets across the country that includes Albertsons, Safeway, Vons, Jewel-Osco, ACME, Shaw’s, Tom Thumb, United Supermarkets, United Express, Randalls, Albertson’s Market, Pavilions, Star Markets, Market Street, Carrs, Haggen, Lucky, Amigos, Andronico’s Community Markets, King’s, Balducci’s, and Albertson’s Market Street. The organization includes 2,230 stores, 23 distribution facilities, and 20 manufacturing plants with over 300,000 employees across 34 states and the District of Columbia. We want talented individuals to be a part of this journey! We have a new vision: forging a retail winner that is admired for national strength with deep local roots, that offers an easy, fun, friendly, and inspiring experience, no matter how a customer chooses to shop with us.
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